Wednesday, September 21, 2016

Dr Scholl's Essentials Cracked Skin Repair


Generic Name: topical emollients (TOP i kal ee MOL i ents)

Brand Names: Aloe Vesta Cream, AlphaSoft, AmeriPhor, Aqua Glycolic, Aqua Lube, Aquaphor, Aveeno, Baby Lotion, Baby Oil, Bag Balm, Baza-Pro, Beta Care, Blistex Lip Balm, Carmex, CarraKlenz, CeraVe, CeraVe AM, Cetaphil Lotion, Chap Stick, Citraderm, CoolBottoms, Corn Huskers Lotion, Curel Moisture Lotion, Derma Soothe, Dr Scholl's Essentials Cracked Skin Repair, Eucerin, Herpecin-L, K-Y Jelly, Keri Lotion, Lamisilk Heel Balm, Lubri-Soft, Lubriderm, Mederma, Moisturel, Natural Ice, NeutrapHor, NeutrapHorus Rex, Neutrogena Cleansing, Neutrogena Lotion, Nivea, Nutraderm, Pacquin, Phisoderm, Pretty Feet & Hands, Proshield Skincare Kit, Remedy 4-in-1 Cleansing Lotion, Replens, Secura, Sensi-Care, Soft Sense, St. Ives, Theraplex Lotion, Vaseline Intensive Care


What are Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?

Emollients are substances that moisten and soften your skin.


Topical (for the skin) emollients are used to treat or prevent dry skin. Topical emollients are sometimes contained in products that also treat acne, chapped lips, diaper rash, cold sores, or other minor skin irritation.


There are many brands and forms of topical emollients available and not all are listed on this leaflet.


Topical emollients may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?


You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist before using this medication if you have deep wounds or open sores, swelling, warmth, redness, oozing, bleeding, large areas of skin irritation, or any type of allergy.


What should I discuss with my healthcare provider before using Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?


You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:



  • deep wounds or open sores;




  • swelling, warmth, redness, oozing, or bleeding;




  • large areas of skin irritation;




  • any type of allergy; or



  • if you are pregnant or breast-feeding.

How should I use Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Clean the skin where you will apply the topical emollient. It may help to apply this product when your skin is wet or damp. Follow directions on the product label.


Shake the product container if recommended on the label.

Apply a small amount of topical emollient to the affected area and rub in gently.


If you are using a stick, pad, or soap form of topical emollient, follow directions for use on the product label.


Do not use this product over large area of skin. Do not apply a topical emollient to a deep puncture wound or severe burn without medical advice.

If your skin appears white or gray and feels soggy, you may be applying too much topical emollient or using it too often.


Some forms of topical emollient may be flammable and should not be used near high heat or open flame, or applied while you are smoking.

Store as directed away from moisture, heat, and light. Keep the bottle, tube, or other container tightly closed when not in use.


What happens if I miss a dose?


Since this product is used as needed, it does not have a daily dosing schedule. Seek medical advice if your condition does not improve after using a topical emollient.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?


Avoid getting topical emollients in your eyes, nose, or mouth. If this does happen, rinse with water. Avoid exposure to sunlight or tanning beds. Some topical emollients can make your skin more sensitive to sunlight or UV rays.

Dr Scholl's Essentials Cracked Skin Repair (topical emollients) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using the topical emollient and call your doctor if you have severe burning, stinging, redness, or irritation where the product was applied.

Less serious side effects are more likely, and you may have none at all.


This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Dr Scholl's Essentials Cracked Skin Repair (topical emollients)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied products. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



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Compare Dr Scholl's Essentials Cracked Skin Repair with other medications


  • Dry Skin


Where can I get more information?


  • Your pharmacist can provide more information about topical emollients.


dexchlorpheniramine, methscopolamine, and phenylephrine


Generic Name: dexchlorpheniramine, methscopolamine, and phenylephrine (DEX klor fen IR a meen, METH skoe POL a meen, FEN il EFF rin)

Brand Names: DexPhen M, Extendryl, Re-Drylex


What is dexchlorpheniramine, methscopolamine, and phenylephrine?

Dexchlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Methscopolamine is an anticholinergic (an-tye-kol-in-URJ-ik) that has a drying effect on the nasal passages.


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of dexchlorpheniramine, methscopolamine, and phenylephrine is used to treat runny nose, sneezing, itchy throat, watery eyes, and sinus congestion caused by allergies or the common cold.


This medication is also used to treat skin rash, hives, or swelling caused by an allergic reaction.


Dexchlorpheniramine, methscopolamine, and phenylephrine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about dexchlorpheniramine, methscopolamine, and phenylephrine?


Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cold or allergy medicine before the MAO inhibitor has cleared from your body. You should not take this medication if you are allergic to dexchlorpheniramine, methscopolamine, or phenylephrine, or if you have glaucoma, heart disease, high blood pressure, or a thyroid disorder.

Before you take dexchlorpheniramine, methscopolamine, and phenylephrine, tell your doctor if you have a blockage in your stomach or intestines, kidney disease, diabetes, an enlarged prostate, problems with urination, or if you are over 40 years old.


Do not give this medication to a child younger than 6 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cold or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains dexchlorpheniramine or phenylephrine.

What should I discuss with my health care provider before taking dexchlorpheniramine, methscopolamine, and phenylephrine?


Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cold or allergy medicine before the MAO inhibitor has cleared from your body. You should not take this medication if you are allergic to dexchlorpheniramine, methscopolamine, or phenylephrine, or if you have:

  • glaucoma;




  • heart disease;




  • high blood pressure; or




  • a thyroid disorder.



If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take this medication, tell your doctor if you have:



  • a blockage in your stomach or intestines;



  • kidney disease;


  • diabetes;




  • an enlarged prostate;




  • problems with urination; or




  • if you are over 40 years old;




FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether dexchlorpheniramine, methscopolamine, and phenylephrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 6 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Older adults may be more likely to have side effects from this medicine.

How should I take dexchlorpheniramine, methscopolamine, and phenylephrine?


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cold medicine is usually taken for only a short time until your symptoms clear up.


Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Tell your doctor if your symptoms do not improve after a few days of treatment, or if you also have a fever with headache, cough, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.


Store this medicine at room temperature, away from heat, light, and moisture.

See also: Dexchlorpheniramine, methscopolamine, and phenylephrine dosage (in more detail)

What happens if I miss a dose?


Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, extreme drowsiness, confusion, weak or shallow breathing, and seizure (convulsions).


What should I avoid while taking dexchlorpheniramine, methscopolamine, and phenylephrine?


This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


Do not use any other over-the-counter cold, cough, or allergy medication without first asking your doctor or pharmacist. Dexchlorpheniramine and phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains dexchlorpheniramine or phenylephrine. Avoid drinking alcohol. It can add to drowsiness caused by an antihistamine.

Dexchlorpheniramine, methscopolamine, and phenylephrine side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • slow heart rate;




  • fast, pounding, or uneven heartbeats;




  • severe dizziness, anxiety, restless feeling, or nervousness;




  • painful or difficult urination;




  • urinating less than usual or not at all; or




  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).



Less serious side effects may include:



  • blurred vision;




  • dizziness, drowsiness, feeling irritable;




  • restlessness or excitability (especially in children);




  • dry mouth, trouble swallowing;




  • nausea, constipation; or




  • warmth, tingling, or redness under your skin.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


Dexchlorpheniramine, methscopolamine, and phenylephrine Dosing Information


Usual Adult Dose for Nasal Congestion:

Dexchlorpheniramine/methscopolamine/PE 1 mg-1.25 mg-10 mg/5 mL oral syrup:
10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Usual Adult Dose for Sinus Symptoms:

Dexchlorpheniramine/methscopolamine/PE 1 mg-1.25 mg-10 mg/5 mL oral syrup:
10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Usual Pediatric Dose for Nasal Congestion:

Dexchlorpheniramine/methscopolamine/PE 1 mg-1.25 mg-10 mg/5 mL oral syrup:
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Usual Pediatric Dose for Sinus Symptoms:

Dexchlorpheniramine/methscopolamine/PE 1 mg-1.25 mg-10 mg/5 mL oral syrup:
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.


What other drugs will affect dexchlorpheniramine, methscopolamine, and phenylephrine?


Tell your doctor about all other medications you use, especially:



  • guanethidine (Ismelin);




  • mecamylamine (Inversine);




  • methyldopa (Aldomet);




  • reserpine; or




  • a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), esmolol (Brevibloc), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;



This list is not complete and there may be other drugs that can interact with dexchlorpheniramine, methscopolamine, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More dexchlorpheniramine, methscopolamine, and phenylephrine resources


  • Dexchlorpheniramine, methscopolamine, and phenylephrine Dosage
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Compare dexchlorpheniramine, methscopolamine, and phenylephrine with other medications


  • Nasal Congestion
  • Sinus Symptoms


Where can I get more information?


  • Your pharmacist can provide more information about dexchlorpheniramine, methscopolamine, and phenylephrine.


Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid


Pronunciation: dex-brome-fen-EER-a-meen/dex-troe-meth-OR-fan/gwye-FEN-e-sin/sue-doe-e-FED-rin
Generic Name: Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine
Brand Name: Deka


Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, cough, and throat and airway irritation due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid is an antihistamine, decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid if:


  • you are allergic to any ingredient in Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid

  • you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid:


Some medical conditions may interact with Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your bladder, stomach, or intestines, ulcers, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid may be increased

  • Digoxin or droxidopa because risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid:


Use Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid may be taken with or without food.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid.



Important safety information:


  • Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid. Using Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid without checking with your doctor.

  • Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid contains dexbrompheniramine, dextromethorphan, and pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains dexbrompheniramine, dextromethorphan, or pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid.

  • Use Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid, discuss with your doctor the benefits and risks of using Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid during pregnancy. It is unknown if Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid is excreted in breast milk. Do not breast-feed while taking Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid.


Possible side effects of Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid:

Store Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid out of the reach of children and away from pets.


General information:


  • If you have any questions about Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid, please talk with your doctor, pharmacist, or other health care provider.

  • Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dexbrompheniramine/Dextromethorphan/Guaifenesin/Pseudoephedrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

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Denorex


Generic Name: coal tar topical (KOL TAR TOP ik al)

Brand Names: Balnetar, Betatar Gel, Coal Tar, Cutar, Denorex, Denorex Dry Scalp, Denorex Extra Strength, Denorex Medicated Shampoo and Conditioner, DHS Tar Shampoo, Doak Tar, Doak Tar Oil, Elta Tar, Fototar, G-TAR, Ionil T, Ionil T Plus, MG 217 Psoriasis, MG217 Medicated Tar, Neutrogena T/Derm, Neutrogena T/Gel, Neutrogena T/Gel Extra Strength, Oxipor VHC, PC Tar, Pentrax, Pentrax Gold, Polytar, Psoriasin, Psorigel, T/Gel Conditioner, Tegrin Medicated, Tegrin Medicated Soap, Therapeutic, Theraplex T, Zetar


What is coal tar?

Coal tar is a by-product of coal processing.


Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


Coal tar may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


What should I discuss with my health care provider before using coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether coal tar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients.


How should I use coal tar?


Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.


Apply coal tar cream, lotion, ointment, or solution according the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day.


To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall.


Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar shampoo may discolor blond or colored hair. This effect is usually temporarily.


Some forms of coal tar can stain fabric or other surfaces.


Store coal tar at room temperature away from moisture and heat. Keep the medicine tightly closed with not in use.

What happens if I miss a dose?


Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a coal tar overdose are not known.


What should I avoid while using coal tar?


Avoid getting this medication in your eyes. If this does occur, rinse with water.

Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result.

Coal tar side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin.

Less serious side effects may include mild skin irritation or skin rash.


This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect coal tar?


Do not use coal tar together with other psoriasis medications unless your doctor tells you to.

There may be other drugs that can interact with coal tar. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Denorex resources


  • Denorex Side Effects (in more detail)
  • Denorex Use in Pregnancy & Breastfeeding
  • Denorex Support Group
  • 4 Reviews for Denorex - Add your own review/rating


  • Denorex Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Denorex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Coal Tar Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Doak Tar Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Fototar Ointment MedFacts Consumer Leaflet (Wolters Kluwer)

  • MG217 Medicated Tar Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Psoriasin Prescribing Information (FDA)



Compare Denorex with other medications


  • Dermatitis
  • Psoriasis
  • Seborrheic Dermatitis


Where can I get more information?


  • Your pharmacist can provide more information about coal tar.

See also: Denorex side effects (in more detail)


Diclofenac Drops



Pronunciation: dye-KLOE-fen-ak
Generic Name: Diclofenac
Brand Name: Voltaren


Diclofenac Drops are used for:

Treating pain, redness, swelling, and sensitivity to light, which are symptoms related to certain eye surgeries. It may also be used for other conditions as determined by your doctor.


Diclofenac Drops are a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing chemicals in the body that cause pain and inflammation.


Do NOT use Diclofenac Drops if:


  • you are allergic to any ingredient in Diclofenac Drops

  • you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to another NSAID (eg, ibuprofen, naproxen, celecoxib) or aspirin

Contact your doctor or health care provider right away if any of these apply to you.



Before using Diclofenac Drops:


Some medical conditions may interact with Diclofenac Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have bleeding or clotting problems or you are taking medicine that prolongs bleeding times (eg, warfarin, heparin)

  • if you have diabetes, rheumatoid arthritis, or other eye problems (eg, dry eye, glaucoma or increased eye pressure)

Some MEDICINES MAY INTERACT with Diclofenac Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Topical corticosteroids for the eye (eg, dexamethasone) because the eye may not be able to heal well

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diclofenac Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Diclofenac Drops:


Use Diclofenac Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Diclofenac Drops are only for the eye. Do not get it in your nose or mouth.

  • To use Diclofenac Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

  • Wait at least 5 minutes after using Diclofenac Drops before using another medicine in the eye.

  • Do not wear contact lenses while you are using Diclofenac Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. The one exception is use of a bandage hydrogel soft contact lens during the first 3 days after refractive surgery. Use of hard contact lenses is not recommended.

  • If you miss a dose of Diclofenac Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Diclofenac Drops.



Important safety information:


  • Diclofenac Drops may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Diclofenac Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Diclofenac Drops has diclofenac in it. Before you start any new medicine, check the label to see if it has diclofenac or another nonsteroidal anti-inflammatory drug (NSAID) medicine in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • Diclofenac Drops should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diclofenac Drops while you are pregnant. It is not known if Diclofenac Drops are found in breast milk. Do not breast-feed while using Diclofenac Drops.


Possible side effects of Diclofenac Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Burning or stinging; change in tear production; discharge; eye redness, irritation, or itching.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred or distorted vision; eye infection; eyelid swelling or redness; sensitivity to glare or light; severe or persistent eye irritation.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Diclofenac Drops:

Store Diclofenac Drops at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in the original container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diclofenac Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Diclofenac Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Diclofenac Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Diclofenac Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Diclofenac resources


  • Diclofenac Use in Pregnancy & Breastfeeding
  • Diclofenac Drug Interactions
  • Diclofenac Support Group
  • 0 Reviews for Diclofenac - Add your own review/rating


Compare Diclofenac with other medications


  • Conjunctivitis
  • Corneal Ulcer
  • Inhibition of Intraoperative Miosis
  • Keratoconjunctivitis
  • Postoperative Ocular Inflammation

daunorubicin Intravenous


daw-noe-ROO-bi-sin


Intravenous route(Solution;Powder for Solution)

Must be given into a rapidly flowing intravenous infusion and must never be given by the intramuscular or subcutaneous route as severe local tissue necrosis will occur if there is extravasation during administration. Myocardial toxicity manifested in its most severe form by potentially fatal congestive heart failure may occur either during therapy or months to years after termination of therapy. The incidence of myocardial toxicity increases after a total cumulative dose exceeding 400 to 550 mg/m(2) in adults, 300 mg/m(2) in children more than 2 years of age, or 10 mg/kg in children less than 2 years of age. Severe myelosuppression occurs when used in therapeutic doses; this may lead to infection or hemorrhage. Dosage should be reduced in patients with impaired hepatic or renal function .



Commonly used brand name(s)

In the U.S.


  • Cerubidine

Available Dosage Forms:


  • Powder for Solution

  • Solution

Therapeutic Class: Antineoplastic Agent


Chemical Class: Anthracycline


Uses For daunorubicin


Daunorubicin belongs to the general group of medicines known as antineoplastics. It is used to treat some kinds of cancer.


Daunorubicin seems to interfere with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by daunorubicin, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.


Before you begin treatment with daunorubicin, you and your doctor should talk about the good daunorubicin will do as well as the risks of using it.


Daunorubicin is to be administered only by or under the immediate supervision of your doctor.


Before Using daunorubicin


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For daunorubicin, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to daunorubicin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Although daunorubicin is used in children, there is no specific information comparing use in children with use in other age groups.


Geriatric


Heart problems are more likely to occur in the elderly, who are usually more sensitive to the effects of daunorubicin. The elderly may also be more likely to have blood problems.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersDStudies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking daunorubicin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using daunorubicin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Rotavirus Vaccine, Live

Using daunorubicin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Adenovirus Vaccine Type 4, Live

  • Adenovirus Vaccine Type 7, Live

  • Bacillus of Calmette and Guerin Vaccine, Live

  • Influenza Virus Vaccine, Live

  • Measles Virus Vaccine, Live

  • Mumps Virus Vaccine, Live

  • Rotavirus Vaccine, Live

  • Rubella Virus Vaccine, Live

  • Smallpox Vaccine

  • Trastuzumab

  • Typhoid Vaccine

  • Varicella Virus Vaccine

  • Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of daunorubicin. Make sure you tell your doctor if you have any other medical problems, especially:


  • Chickenpox (including recent exposure) or

  • Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body

  • Gout (history of) or

  • Kidney stones—Daunorubicin may increase uric acid in the body, which can cause gout or kidney stones

  • Heart disease—Risk of heart problems caused by daunorubicin may be increased

  • Infection—Daunorubicin can decrease your body's ability to fight infection

  • Kidney disease or

  • Liver disease—Effects of daunorubicin may be increased because of slower removal from the body

Proper Use of daunorubicin


Daunorubicin is sometimes given together with certain other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by mouth, ask your health care professional to help you plan a way to take them at the right times.


While you are receiving daunorubicin, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.


daunorubicin often causes nausea and vomiting. However, it is very important that you continue to receive it, even if you begin to feel ill. Ask your health care professional for ways to lessen these effects.


Dosing


The dose of daunorubicin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of daunorubicin. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


Precautions While Using daunorubicin


It is very important that your doctor check your progress at regular visits to make sure that daunorubicin is working properly and to check for unwanted effects.


While you are being treated with daunorubicin, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Daunorubicin may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have taken oral polio vaccine. Do not get close to them, and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.


Daunorubicin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:


  • If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

  • Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.

  • Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.

  • Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.

  • Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.

  • Avoid contact sports or other situations where bruising or injury could occur.

If daunorubicin accidentally seeps out of the vein into which it is injected, it may damage some tissues and cause scarring. Tell the doctor or nurse right away if you notice redness, pain, or swelling at the place of injection.


daunorubicin Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.



Check with your doctor immediately if any of the following side effects occur:


Less common
  • Cough or hoarseness

  • fever or chills

  • irregular heartbeat

  • lower back or side pain

  • pain at place of injection

  • painful or difficult urination

  • shortness of breath

  • swelling of feet and lower legs

Rare
  • Black, tarry stools

  • blood in urine or stools

  • pinpoint red spots on skin

  • unusual bleeding or bruising

Check with your doctor as soon as possible if any of the following side effects occur:


More common
  • Sores in mouth and on lips

Less common
  • Joint pain

Rare
  • Skin rash or itching

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Nausea and vomiting

Less common or rare
  • Darkening or redness of skin

  • diarrhea

Daunorubicin causes the urine to turn reddish in color, which may stain clothes. This is not blood. It is perfectly normal and lasts for only 1 or 2 days after each dose is given.


daunorubicin often causes a temporary and total loss of hair. After treatment with daunorubicin has ended, normal hair growth should return.


After you stop using daunorubicin, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:


  • Irregular heartbeat

  • shortness of breath

  • swelling of feet and lower legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More daunorubicin Intravenous resources


  • Daunorubicin Intravenous Use in Pregnancy & Breastfeeding
  • Daunorubicin Intravenous Drug Interactions
  • Daunorubicin Intravenous Support Group
  • 0 Reviews for Daunorubicin Intravenous - Add your own review/rating


Compare daunorubicin Intravenous with other medications


  • Acute Lymphocytic Leukemia
  • Acute Myeloid Leukemia
  • Acute Nonlymphocytic Leukemia

Tuesday, September 20, 2016

Dexamethasone Intensol


Generic Name: dexamethasone (Oral route)

dex-a-METH-a-sone

Commonly used brand name(s)

In the U.S.


  • Baycadron Elixer

  • Decadron

  • Dekpak 13 Day Taperpak

  • Dexamethasone Intensol

  • DexPak

  • DexPak 10 Day TaperPak

  • DexPak Jr

  • Zema-Pak

Available Dosage Forms:


  • Solution

  • Elixir

  • Tablet

Therapeutic Class: Endocrine-Metabolic Agent


Pharmacologic Class: Adrenal Glucocorticoid


Uses For Dexamethasone Intensol


Dexamethasone provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, kidney problems, skin conditions, and flare-ups of multiple sclerosis. Dexamethasone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.


This medicine is available only with your doctor's prescription.


Before Using Dexamethasone Intensol


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of dexamethasone in children. However, pediatric patients are more likely to have slower growth and bone problems if dexamethasone is used for a long time. Recommended doses should not be exceeded, and the patient should be carefully monitored during therapy.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dexamethasone in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for elderly patients receiving dexamethasone.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Praziquantel

  • Rilpivirine

  • Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Aldesleukin

  • Boceprevir

  • Bupropion

  • Darunavir

  • Dasatinib

  • Efavirenz

  • Etravirine

  • Fosamprenavir

  • Imatinib

  • Ixabepilone

  • Lapatinib

  • Nevirapine

  • Nilotinib

  • Quetiapine

  • Rivaroxaban

  • Romidepsin

  • Sunitinib

  • Telaprevir

  • Temsirolimus

  • Thalidomide

  • Ticagrelor

  • Vandetanib

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alatrofloxacin

  • Alcuronium

  • Aminoglutethimide

  • Aprepitant

  • Aspirin

  • Atracurium

  • Balofloxacin

  • Caspofungin

  • Cinoxacin

  • Ciprofloxacin

  • Clinafloxacin

  • Enoxacin

  • Fleroxacin

  • Fluindione

  • Flumequine

  • Fosaprepitant

  • Fosphenytoin

  • Gallamine

  • Gemifloxacin

  • Grepafloxacin

  • Hexafluorenium

  • Itraconazole

  • Levofloxacin

  • Licorice

  • Lomefloxacin

  • Metocurine

  • Moxifloxacin

  • Norfloxacin

  • Ofloxacin

  • Pancuronium

  • Pefloxacin

  • Phenobarbital

  • Phenytoin

  • Primidone

  • Prulifloxacin

  • Rifampin

  • Rifapentine

  • Ritonavir

  • Rosoxacin

  • Rufloxacin

  • Saiboku-To

  • Sparfloxacin

  • Temafloxacin

  • Tosufloxacin

  • Trovafloxacin Mesylate

  • Vecuronium

  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Cataracts or

  • Congestive heart failure or

  • Cushing's syndrome (adrenal gland problem) or

  • Diabetes or

  • Eye infection or

  • Fluid retention or

  • Glaucoma or

  • Hyperglycemia (high blood sugar) or

  • Hypertension (high blood pressure) or

  • Infection (eg, bacterial, virus, fungus) or

  • Mood changes, including depression or

  • Myasthenia gravis (severe muscle weakness) or

  • Osteoporosis (weak bones) or

  • Peptic ulcer, active or history of or

  • Personality changes or

  • Stomach or intestinal problems (eg, diverticulitis, ulcerative colitis) or

  • Tuberculosis, inactive—Use with caution. May make these conditions worse.

  • Fungal infections or

  • Herpes simplex eye infection—Should not be used in patients with these conditions.

Proper Use of dexamethasone

This section provides information on the proper use of a number of products that contain dexamethasone. It may not be specific to Dexamethasone Intensol. Please read with care.


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance for unwanted effects.


Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.


The Dexamethasone Intensol™ solution is a concentrated liquid. Measure the concentrated liquid with the special oral dropper that comes with the package. The liquid should be added to water, juice, soda or a soda-like beverage, applesauce, or pudding. Stir the mixture well and drink or eat it right away. Do not store the mixture for future use.


If you use this medicine for a long time, do not suddenly stop using it without checking first with your doctor. You may need to slowly decrease your dose before stopping it completely.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage forms (solution, tablets):
    • Dose depends on medical condition:
      • Adults—At first, 0.75 to 9 milligrams (mg) per day. Your doctor may adjust your dose as needed.

      • Children—Dose is based on body weight and must be determined by your doctor. At first, 0.02 to 0.3 mg per kilogram (kg) of body weight per day, divided and taken 3 or 4 times a day. Your doctor may adjust your dose as needed.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Throw away any unused Dexamethasone Intensol™ solution 90 days after the bottle is opened for the first time.


Precautions While Using Dexamethasone Intensol


If you will be taking this medicine for a long time, it is very important that your doctor check you at regular visits for any unwanted effects that may be caused by this medicine. Blood or urine tests may be needed to check for unwanted effects.


Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.


If you are using this medicine for a long time, tell your doctor about any extra stress or anxiety in your life, including other health concerns and emotional stress. Your dose of this medicine might need to be changed for a short time while you have extra stress.


Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor right away if you have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.


While you are being treated with dexamethasone, do not have any immunizations (vaccines) without your doctor's approval. Dexamethasone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor.


Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).


This medicine might cause thinning of the bones (osteoporosis) or slow growth in children if used for a long time. Tell your doctor if you have any bone pain or if you have an increased risk for osteoporosis. If your child is using this medicine, tell the doctor if you think your child is not growing properly.


This medicine may cause changes in mood or behavior for some patients. Tell your doctor right away if you have depression; mood swings; a false or unusual sense of well-being; trouble with sleeping; or personality changes while taking this medicine.


Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain skin tests.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Dexamethasone Intensol Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Aggression

  • agitation

  • anxiety

  • blurred vision

  • decrease in the amount of urine

  • dizziness

  • fast, slow, pounding, or irregular heartbeat or pulse

  • headache

  • irritability

  • mental depression

  • mood changes

  • nervousness

  • noisy, rattling breathing

  • numbness or tingling in the arms or legs

  • pounding in the ears

  • shortness of breath

  • swelling of the fingers, hands, feet, or lower legs

  • trouble thinking, speaking, or walking

  • troubled breathing at rest

  • weight gain

Incidence not known
  • Abdominal cramping and/or burning (severe)

  • abdominal pain

  • backache

  • bloody, black, or tarry stools

  • cough or hoarseness

  • darkening of skin

  • decrease in height

  • decreased vision

  • diarrhea

  • dry mouth

  • eye pain

  • eye tearing

  • facial hair growth in females

  • fainting

  • fatigue

  • fever or chills

  • flushed, dry skin

  • fractures

  • fruit-like breath odor

  • full or round face, neck, or trunk

  • heartburn and/or indigestion (severe and continuous)

  • increased hunger

  • increased thirst

  • increased urination

  • loss of appetite

  • loss of sexual desire or ability

  • lower back or side pain

  • menstrual irregularities

  • muscle pain or tenderness

  • muscle wasting or weakness

  • nausea

  • pain in back, ribs, arms, or legs

  • painful or difficult urination

  • skin rash

  • sleeplessness

  • sweating

  • trouble healing

  • trouble sleeping

  • unexplained weight loss

  • unusual tiredness or weakness

  • vision changes

  • vomiting

  • vomiting of material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Increased appetite

Incidence not known
  • Abnormal fat deposits on the face, neck, and trunk

  • acne

  • dry scalp

  • lightening of normal skin color

  • red face

  • reddish purple lines on the arms, face, legs, trunk, or groin

  • swelling of the stomach area

  • thinning of the scalp hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



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